IndraLab

Statements


KCNMA1 activates LDL. 2 / 2
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"Enhancement of both the SLO mediated LDL oxidation and the conversion of LDL to a cytotoxin was observed when either superoxide dismutase or copper (II) (3,5,-diisopropylsalicylic acid) 2, both of which dismute superoxide anion, were included during the incubation of SLO with LDL."

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"Thus, purified lipoxygenase can mediate LDL modification and superoxide anion inhibits this reaction, Furthermore, H2O2 is essential for SLO mediated LDL oxidation and conversion of LDL to a cytotoxin."