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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

STAMBP activates STAM. 2 / 4

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"The gene encoding AMSH (associated molecule with a Src homology 3 domain), a deubiquitinating enzyme, was up-regulated as well as, three genes involved in the ESCRT pathway, ESCRT-0 (STAM (signal transducing adaptor molecule)) and ESCRT-III (CHMP (charged multivesicular body proteins) 2 and 4)."

29023475

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"Further, the DUB activity of STAMBP modulates the ubiquitination of ESCRT proteins STAM and hepatocyte growth factor regulated tyrosine kinase substrate (HRS), but does not affect their degradation or stability XREF_BIBR XREF_BIBR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...