IndraLab

Statements

STAMBP activates STAM. 2 / 4
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"The gene encoding AMSH (associated molecule with a Src homology 3 domain), a deubiquitinating enzyme, was up-regulated as well as, three genes involved in the ESCRT pathway, ESCRT-0 (STAM (signal transducing adaptor molecule)) and ESCRT-III (CHMP (charged multivesicular body proteins) 2 and 4)."
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"Further, the DUB activity of STAMBP modulates the ubiquitination of ESCRT proteins STAM and hepatocyte growth factor regulated tyrosine kinase substrate (HRS), but does not affect their degradation or stability XREF_BIBR XREF_BIBR."
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