IndraLab

Statements

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"Axonal sorting is supported by proper SC differentiation (Jessen and Mirsky 2005) while JAB1 deletion led to delayed or arrested SC differentiation which was associated with abnormally increased level of p27 (Porrello et al. 2014)."
37365502
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"Dominant negatives of both JAB-1 and cytohesin-1 inhibited interleukin 2 production and impaired T helper type 1 differentiation."
14528303
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"In fact, Jab1 -/- nerves show reduced Schwann cell number and increased p27 levels, whereas genetic reduction of p27 in Jab1 -/- mice almost rescues Schwann cell number, differentiation, and the axonal sorting defect."
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