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COPS5 inhibits cell differentiation. 2 / 2

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"In fact, Jab1 -/- nerves show reduced Schwann cell number and increased p27 levels, whereas genetic reduction of p27 in Jab1 -/- mice almost rescues Schwann cell number, differentiation, and the axonal sorting defect."

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"Dominant negatives of both JAB-1 and cytohesin-1 inhibited interleukin 2 production and impaired T helper type 1 differentiation."

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COPS5 inhibits cell differentiation. 2 / 2

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