IndraLab

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"It was found that about 100% of patients treated with Hydroxychloroquine in combination with Azithromycin were cured, while about 57.1% of patients treated with Hydroxychloroquine alone were cured XREF_BIBR."
| PMC
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"Results showed that the virus was not found after 6days in all the patients treated with HCQ and azithromycin, in 57.1% of the patients treated with HCQ only, and in 12.5% of the control group patients (p < 0.001)."
| PMC
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"A substantial reduction in viral load and more rapid virus elimination was seen in patients treated with a combination of hydroxychloroquine and azithromycin; however, the majority of patients treated with hydroxychloroquine alone continued to display symptoms of upper or lower respiratory tract infections [XREF_BIBR]."
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"A small and poorly controlled French trial reported viral clearance at day 6 in 100% of COVID-19 patients treated with hydroxychloroquine and azithromycin, compared to 57% treated with hydroxychloroquine alone, and 13% in controls (Gautret et al."
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"On the sixth day from the beginning of treatment, all patients undergoing with hydroxychloroquine and azithromycin combination were clinically cured compared to 57.1% of patients treated with hydroxychloroquine alone."
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"A French paper reporting on the use of drug combinations in infected patients highlighted the possibility that hydroxychloroquine is effective in the treatment of COVID-19 patients [ 4 ] particularly in combination with azithromycin ."
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"The reported effects of azithromycin are thus often derived from patients treated with hydroxychloroquine-azithromycin combination versus hydroxychloroquine alone."
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"They reported that the duration of hospital stay was higher in patients who were treated with both hydroxychloroquine and azithromycin compared to those who were only treated with hydroxychloroquine; but this difference was non significant (10.3 vs 9.6, Odds ratio :0.7, 95% CI : -0.6 -1.9) XREF_BIBR."
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"The study revealed that at day 6 post-inclusion, 100% of the patients treated with the combination of hydroxychloroquine and azithromycin were cured, compared with 57.1% of the patients treated with hydroxychloroquine only, and 12.5% of the control patients."
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"He was continued on azithromycin and ceftriaxone and treated with hydroxychloroquine 400mg daily."
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"Out of 156 children, 78 (50%) children received Hydroxychloroquine containing regimen, 15 of them were treated with hydroxychloroquine + azithromycin + oseltamivir, 44 were treated with hydroxychloroquine + azithromycin and 21 were only treated with hydroxychloroquine."
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"Hydroxychloroquine (HCQ) decreases the benefit of anti-PD-1 immune checkpoint blockade in tumor immunotherapy.The anti-malarial 4-aminoquinoline drugs chloroquine (CQ) and hydroxychloroquine (HCQ) as well as the antibiotic azithromycin (AZ) have gained much attention as potential therapies."
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"On the other hand, HCQ was then added at a concentration of 6 μg/mL to each increased levels of DOXY i.e. 0.2, 2, 10, 100, and 400 μg/mL to produce HCQ 6 μg/mL + DOXY.Fig 9: The cytotoxicities of Favipiravir (FAVI) and Azithromycin (AZI) as a single drug (left) and dual drug combination in constant and non-constant ratios (right) analysed by using CompuSyn Software (n = 3)."
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"This same study observed no improvements in pulmonary images or in the average length of hospital stay after combining with other antivirals (Arbidol + Ritonavir or Interferon + LPV/r or Interferon + Darunavir).3.4.2 Hydroxychloroquine and Azithromycin Patients treated with Hydroxychloroquine (HCQ) (ID : 26402) demonstrated areduction in radiological progression of the disease compared to conventional treatment (OR for radiological disease progression during treatment was 0.31; 95% CI, [0, 110.9])."
| DOI