IndraLab

Statements

ADAM17 binds TNFRSF1A. 2 / 3
1 | 2
reach
"The TNF-alpha-converting enzyme TACE can cleave membrane bound TNFR1 and TNFR2 to yield soluble TNF receptors, which have higher affinity for TNF-alpha."
28102063
reach
"Julia and colleagues suggested that TNFR1-dependent tumor cell-induced endothelial cell death, tumor cell extravasation, TNF-induced necroptosis, and subsequent metastatic seeding rely on the activation of the membrane-bound metalloprotease ADAM17."
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