IndraLab

Statements

Paroxetine inhibits KCNK2. 2 / 2
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"Application of 10 muM fluoxetine, 20 muM paroxetine, 100 muM citalopram, and 30 muM chlorpromazine significantly inhibited TREK-1 currents by 28 +/- 11%, 40 +/- 9%, 31 +/- 10%, and 52 +/- 10%, respectively (p < 0.05, XREF_FIG a-c)."
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"Fluoxetine and paroxetine , which are clinically prescribed as antidepressants , are also effective in the reduction of TREK-1 activity [ 23,24,25,26 ] ."
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