IndraLab

Statements

MAPK activates KCNA3. 13 / 13
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"p38 MAPK, through the intermediates MAPK-activated kinase 2 (MK2) and MK3, can activate p90RSK in certain situations, such as viral infection [30,31]."
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"The closely-related mitogen-activated protein kinase-activated protein kinases MK2 and MK3 are involved in both up- and down-regulation of inflammation in mammals and govern the inflammatory response at different regulatory levels of gene expression and with different kinetics."
23832958
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"We demonstrate that the mitogen-activated protein kinase-activated protein kinases (MAPKAPKs) MK2 and MK3 are activated on virus infection and, in their active form, directly interact with the repressor of the inhibitor of PKR p88(rIPK)."
20484669
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"MAPKAPK5/PRAK is a serine/threonine kinase was originally identified based on homology with two other MAP kinase activated kinases, MK2 and MK3 [ xref , xref ]."
26042227
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"This applies to the MAPK-activated protein kinases MK2 and MK3."
19484198
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"MAPK-activated kinases MK2 and MK3 are uniquely activated by p38 MAPK, whereas the mitogen- and stress-activated kinases MSK1 and MSK2 can be activated by either p38 MAPK or ERK."
23028406
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"Downstream substrates for MAPKs are transcription factors (e.g., ATF2, ELK‐1, or c‐Jun), and other protein kinases, such as the MAP kinase‐activated protein kinases MK2 and MK3."
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"This is partially regulated by p38 mitogen-activated protein kinase (MAPK), which further activates two closely related isoforms of the MAPKactivated protein kinases (MKs), MK2 and MK3."
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"Therefore, it can be suggested that MK2 and MK3 altogether affects 311 CHIKV progeny release without affecting viral protein synthesis.The MAPK-activated protein kinases MAPKAPK3 (MK3) and MAPKAPK2 (MK2) In order to confirm the involvement of actin fibers in CHIKV progeny release, Vero cells were 373 virus infected and drug treated as mentioned above and cells were fixed at 18 hpi."
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"The MAPK-activated protein kinases MK2 and MK3, function as sensors of cell injury and exert pivotal roles in IL-33-induced cytokine production by mast cells in inflammatory responses ( xref , xref , xref )."
33488605
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"Those functionally subordinate to p38 include MAPK-activated protein kinases MK2 and MK3 (also called MAPKAP-K2 and MAPKAP-K3), mitogen- and stress-activated kinases MSK1 and MSK2, and MAPK-interacting kinases MNK1 and MNK2."
19740675
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"Using this assay, we quantitatively evaluate the role of the MAPK-activated protein kinases MK2 and MK3 in fibroblast migration."
19743408
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"Based on structural and functional homology, the MAPKAPKs are divided in four subfamilies: ribosomal S6 kinase (RSK) with the members RSK1-4; mitogen- and stress-activated kinase (MSK) comprising MSK1 and MSK2; MAPK-interacting protein kinase (MNK) including MNK1 and MNK2, and the MAPK-activated protein kinases (MAPKAPK) MK2, MK3 and MK5 [ xref - xref ]."
21575178