IndraLab

Statements


| 3

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"If IKKbeta is the only target of curcumin, curcumin should not inhibit LPS (TLR4 agonist)-induced activation of TRIF pathway of TLR4."

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"Therefore, curcumin inhibits LPS induced activation of both MyD88- and TRIF dependent pathways of TLR4 resulting in the inhibition of both NF-kappaB and IRF3."

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"However, it is not known whether curcumin inhibits TRIF dependent pathway or not."