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Statements

Calcium(2+) activates KCNQ1. 8 / 8
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"By contrast, recent studies showing that KCNQ1 and I KS (KCNQ1/KCNE1) currents are stimulated by increases in intracellular Ca 2+ and are markedly inhibited by calmodulin antagonists [15] ."
16876114
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"Elevations in the levels of cAMP, cyclic guanosine monophosphate (cGMP), and Ca 2+ activate apical Cl - channels (CFTR and CaCC) and basolateral K + channels (KCNQ1 and KNE3, KCNN4)."
22850599
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"In another example, intracellular Ca 2+ binds to BK type K + channels to increase channel activation ( 130 )."
26745405
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"It is well established that LQT and CPVT can be caused by improper function of Ca 1.2 and RyR2 [38]."
32093079
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"As we will consider further, modulation of KCNE1 and KCNQ1 channel complexes by ATP and Ca ++ may constitute a protective mechanism against NIHL."
18790034
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"They have been shown to activate large-conductance calcium activated potassium (BK) channels and the heteromultimeric KCNQ1 and KCNE1 (I Ks) channels."
20097192
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"1 The cAMP and Ca 2+ -dependent Cl − secretion involves different types of apical Cl − channels and basolateral K + channels, namely, cystic fibrosis transmembrane conductance regulator (CFTR) and cal[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28651800
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"These results suggest that the specific lack of external Ca triggers the large visible inactivation of WT Kv7.1."
33355140