IndraLab

Statements


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"They have been shown to activate large-conductance calcium activated potassium (BK) channels and the heteromultimeric KCNQ1 and KCNE1 (I Ks) channels."

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"Elevations in the levels of cAMP, cyclic guanosine monophosphate (cGMP), and Ca 2+ activate apical Cl - channels (CFTR and CaCC) and basolateral K + channels (KCNQ1 and KNE3, KCNN4)."

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"It is well established that LQT and CPVT can be caused by improper function of Ca 1.2 and RyR2 [38]."

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"As we will consider further, modulation of KCNE1 and KCNQ1 channel complexes by ATP and Ca ++ may constitute a protective mechanism against NIHL."