IndraLab

Statements

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"Furthermore, BK channel activation by LPS should always be suppressed by NOS inhibitors, regardless of the protocol used for cell isolation."
11557024
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"Kinetic analysis showed that both LPS and SNP increased Po by accelerating the rate of BK channel reopening, rather than by retarding the closure of open channels."
9484848
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"Within 30 s, LPS markedly increased the open probability of the single BK channel in this membrane patch."
11557024
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"These observations indicated that LPS increased BK channel open probability by accelerating the rate of reopening from long duration channel closures."
11557024
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"Performing patch-clamp experiments on human macrophages, we show that the K (+) channel MaxiK is activated by lipopolysaccharide, peptidoglycan, and interleukin-1."
16790810
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"Possible pathways include the activation of MaxiK channels, which are activated by LPS and facilitate potassium efflux without involvement of the pannexin-1/ATP/P2X 7 axis (XREF_FIG)."
28246166
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"MaxiK can be activated by agonistically active LPS, and activation can be completely inhibited by LPS antagonists (e.g. synthetic compound 406) and by anti-CD14 antibodies."
12831460