IndraLab

Statements

Morphine(1+) inhibits NLRP3. 3 / 3
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"Inhibition of spinal P2X7R with A438079 not only prevented the development of morphine induced tolerance but also inhibited repeated morphine treatment induced upregulation of spinal NLRP3."
33061523
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"In vivo, intra-gastric administration of procyanidins reduced morphine induced activation of NLRP3 and IL-1beta, likely through inhibition of p38 kinase [XREF_BIBR]."
33782649
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"Knockout of TLR4 alleviated morphine tolerance and chronic morphine induced upregulation of spinal NLRP3."
33061523