IndraLab

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GSK3B phosphorylates USP27X. 4 / 4
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"For example, glycogen synthase kinase 3 beta (GSK3β) can directly bind to and phosphorylate USP27X, thereby enhancing the interaction between USP27X and CBX2 (Xing et al. 2023)."
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"Furthermore, it has been revealed that glycogen synthase kinase 3 beta (GSK3beta) can directly bind to and phosphorylate USP27X, thereby enhancing the interaction between USP27X and CBX2 and leading to further stabilization of the CBX2 protein."
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"GSK3beta enhances the stability of CBX2 protein by phosphorylating USP27X."
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"Phosphorylation of USP27X by GSK3beta maintains the stability and oncogenic functions of CBX2."
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