IndraLab

Statements

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"Strikingly, we observed that USP6 inhibited growth of Ewing sarcoma tumors when xenografted into nude but not NOD scid gamma (NSG) mice, implicating a role for the innate immune system in mediating the tumor-suppressive function of USP6 (20)."
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"Here we report that natural killer (NK) cells are essential for its tumor-inhibitory functions, as NK cell depletion reverses USP6-mediated suppression of Ewing sarcoma xenograft growth."
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"NK Cells are Required for Suppression of Ewing Sarcoma Tumor Growth by USP6."
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"We previously demonstrated that USP6 inhibits growth of Ewing sarcoma tumors when xenografted into nude mice, but not NSG mice (20)."
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