IndraLab

Statements

CACNA1A activates CASP3. 4 / 4
| 4
reach
"For ataxias SCA1, SCA2, SCA3, SCA6, SCA7, SCA17 and dentatorubral-pallidoluysian atrophy, expansion beyond 39, 33, 45, 20, 34, 41, and 35 repeats in the ATXN1, ATXN2, ATXN3, CACNA1A, ATXN7, TBP, and ATN1 genes, respectively, will cause disease."
35592702
reach
"XREF_BIBR SCA1, SCA2, Machado-Joseph or SCA3, SCA6, SCA7, SCA12, SCA17, and dentatorubral-pallidoluysian atrophy (DRPLA) are caused by (CAG) n repeat expansions in the ATXN1, ATXN2, ATXN3, CACNA1A, ATXN7, PPP2R2B, TBP, and ATN1 genes, respectively, and all lead to the expansion of a polyglutamine tract in the corresponding proteins."
24780882
reach
"There are also 6 types of spinocerebellar ataxias (SCA1, SCA2, SCA3, SCA6, SCA7, SCA17), which are caused by expansions in the genes ATXN1 , ATXN2 , ATXN3 , CACNA1A , ATXN7 and TBP , respectively."
30597161
reach
"SGIV can induce typical apoptosis in FHM cells and enhance the formation of apoptosis by activating Caspase3 activity [21,31]."
37766214