IndraLab

Statements



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"Transfection of MPM cells with a miR-17-5p mimic or KCNMA1 specific siRNAs reduced mRNA expression of KCa1.1 and inhibited MPM cell migration."

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"KCa1.1, a calcium activated potassium channel subunit alpha 1, is targeted by miR-17-5p and modulates cell migration in malignant pleural mesothelioma."

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"Interestingly, it has been found that irradiation of GBM cells raises the intracellular Ca 2+ concentration and stimulates KCa1.1 channel activity, which result in the activation of CaMKII and enhanced cell migration."