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Fenofibrate inhibits NFKB1. 2 / 2

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"Fenofibrate downregulated p-IKKa/b, p-IkappaBa, and nuclear NFkappaB (p65 and p50), which are involved in the NF-kappaB pathway, and upregulated AMPK related proteins, such as LKB1, p-AMPKalpha, p-AMPKbeta1, and AMPKgamma1."

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"XREF_TABLE and XREF_FIG showed that fenofibrate could significantly inhibit the up-regulation of NF-kappaB p50 and p65 proteins of EAM rats (p < 0.05)."

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Fenofibrate inhibits NFKB1. 2 / 2

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