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MINDY1 leads to the deubiquitination of ESR. 3 / 3
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"As show in Fig. 6A, MINDY1 depletion significantly increased ERα ubiquitylation in MCF-7 cells."

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"We observed that MINDY1 reduced ERα ubiquitylation in MCF-7 cells in a dose-dependent manner (Fig. 6C)."

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"Furthermore, MINDY1 reduced the ubiquitylation of ERα induced by the E3 ligase TRIM8 (Fig. 6D) [26]."