IndraLab

Statements

USP28 activates Notch. 2 / 2

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"USP28 has also been reported to antagonize ubiquitin-dependent degradation of the oncogene product MYC as well as JUN and Notch ."

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"USP28 antagonizes the Ub-dependent degradation of c-myc, as well as c-Jun and Notch, by targeting the Ub ligase Fbw7, thereby stabilizing the HIF-1α transcription factor [66] ."

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IndraLab

Statements

USP28 activates Notch. 2 / 2

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