IndraLab

Statements

PSMD14 inhibits TP53BP1. 3 / 3
| 3
reach
"POH1 activity associated with the proteasome results in cleavage of K63 chains at damage sites, and limits the accumulation of 53BP1 at DSBs."
28587922
reach
"Reduced DNA repair in RNF8-, RNF168- or 53BP1 depleted cells, in which no 53BP1 IRIF form, could be countered by co-depletion of POH1, which restored both repair and 53BP1 IRIF."
23075493
reach
"USP44, USP17L2/DUB3, USP11, ZUFSP and POH1 loss promotes the excessive spreading of Ub at DSBs and concomitant excessive accumulation of 53BP1 [57–65]."
31769469