IndraLab

Statements



reach
"As shown in Figure XREF_FIG, expression of gammaH2AX and cleaved caspase-3, as well as reduction in Rad51 and RIP1 expression and sustained level of IkappaBalpha expression were significantly more enhanced in tumor extracts from animals treated with the inhibitor and TMZ, in comparison to non treated mice and mice treated with the RGD inhibitor or TMZ only, revealing the same molecular mechanism to occur also in vivo."

reach
"Both Ad.Egr-TNF and IR activate nuclear factor-kappaB, and temozolomide inhibits this activity in an inhibitor of kappaBalpha (IkappaBalpha)-independent manner."