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USP13 leads to the deubiquitination of TCRalpha. 1 / 1

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"Although our results have not ruled out the possibility that USP13 may contribute to deubiquitination of TCRalpha with the assistance of a substrate recruiting adaptor in cells, the inability to deubiquitinate TCRalpha by purified USP13 suggests that the accumulation of ubiquitinated TCRalpha in USP13 knockdown cells is probably due to ERAD inhibition at a step downstream of ubiquitination, as shown in Bag6 depleted cells."

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IndraLab

Statements

USP13 leads to the deubiquitination of TCRalpha. 1 / 1

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