IndraLab

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KCNH2-T473P activates dTDP. 1 / 1
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"Genetic mutations in KCNH2 (T473P) and KCNE1 (G38S) increase susceptibility to hypokalemia induced TdP by reducing repolarization reserve and QT interval prolongation, demonstrating a drug independent, genetic predisposition to hypokalemia related TdP risk."