IndraLab

Statements

USP11 activates proteolysis. 4 / 4
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"These results indicate that USP11 may prevent Mgl-1 protein degradation from the 26S proteasome."
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"RanBPM protein degradation was prevented by USP11 resulting in the protein stabilization [16] ."
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"The deubiquitinating activity of USP11 prevents SFTPC protein degradation."
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"This provides us a new perspective for future studies.In conclusion, in our present study, we found that IsoLiPro can lower USP11 protein levels both in vivo and in vitro, mainly through modulating protein degradation without impacting directly the USP11 enzyme activity, and consequently ameliorate AD pathologies in transgenic AD animal model."
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