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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 activates FOXP3. 1 / 1

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"Foxp3 is a critical Tx for Treg polarization and regulated by one of many mechanisms, including ubiquitination-dependent degradation. Deubiquitinase USP7 decreases Foxp3 polyunibiutination and stabilize Foxp3, thus increases Treg-suppressive capacity."

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...