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USP2 inhibits CFLAR. 2 / 2

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"USP2 knockdown via siRNA inhibits actinomycin and TNF-α-induced apoptosis via c-FLIP upregulation in hepatocytes [27]."

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"Compared to its parental cells , the sorafenib-resistant clones express lower levels of USP2 , which presumably caused the aforementioned increase in cFLIP levels and decrease in ITCH levels [ 13,81 ] ."

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Statements

USP2 inhibits CFLAR. 2 / 2

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