IndraLab

Statements

USP8 leads to the ubiquitination of TARDBP. 2 / 2

| 2

reach

"The UBPY RNAi-model shows increased insoluble TDP-43 and enhanced ubiquitination of TDP-43 ( Hans et al., 2014 ), indicating that neurotoxicity induced by TDP-43 is enhanced in the absence of UBPY."

34023421

➶

reach

"In D. melanogaster models, the ubiquitin conjugating enzyme UBE2E3 promotes ubiquitination of TDP-43; in contrast, ubiquitin isopeptidase Y (UBPY) decreased TDP-43 ubiquitination."

27693252

INDRA sources:

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IndraLab

Statements

USP8 leads to the ubiquitination of TARDBP. 2 / 2

INDRA sources:

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