IndraLab

Statements

COPS6 inhibits COPS5. 2 / 2
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"Previous study has shown that over-expression of CSN6 increases its competition with CSN5 in terms of cullin binding, and thereby inhibits accessibility of cullin to CSN5 for deneddylation, which stab[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Notably, the MPN domain of CSN6 inhibited the association of CSN5 with Cullin-1, while the C-terminal domain had less impact (XREF_FIG)."
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