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Statements

USP3 inhibits TLR. 2 / 2

| 2

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"USP3 participates in the establishment of innate immune “tolerance” memory through a non-transcriptional feedback mechanism and negatively regulates TLR/IL1β-induced inflammatory signaling activation by specifically removing the K63-linked polyubiquitin chain on MyD88."

38927085

➶

reach

"The deficiency of USP3 enhances TLR-mediated proinflammatory responses."

37971847

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP3 inhibits TLR. 2 / 2

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