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Tanespimycin inhibits IRF3. 2 / 2

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"Interestingly, we found that geldanamycin and its analog 17-AAG, which was previously known to inhibit IRF3 activation by RNA viruses, block MAVS aggregation."

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"Taken together, these results suggest that geldanamycin and 17-AAG inhibit IRF3 activation by preventing MAVS aggregation on the mitochondria."

21782231

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IndraLab

Statements

Tanespimycin inhibits IRF3. 2 / 2

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