IndraLab

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CDK5 phosphorylates BRCC3. 6 / 6
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"Further studies are needed to determine whether BRCC3 is phosphorylated by Cdk5 to regulate inflammation.This work was supported by the National Natural Science Foundation of China (No. 31660269 ), Na[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Here we studied whether Cdk5 phosphorylates BRCC3."

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"Phosphorylation of BRCC3 by Cdk5 was predicted by GPS 5.0 software."

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"Phosphorylation of BRCC3 fusion protein by Cdk5 in vitro was detected by mass spectrometry and Western blotting."

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"In vitro kinase assay, Western blotting, and mass spectrometry showed that Cdk5 can phosphorylate BRCC3."

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"It has been demonstrated that protein kinase Cdk5 can phosphorylate the deubiquitinating enzyme BRCC3 in vitro, which provides new data for further study on the mechanism of neurodegeneration."