IndraLab

Statements

USP16 activates cell growth. 4 / 4
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"Depletion of USP16 significantly increased the cell growth rate and inhibited cell anoikis in vitro (XREF_FIG and XREF_SUPPLEMENTARY)."
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"Cells proliferation were then analysed using a CCK-8 assay, and the results revealed that knockdown of USP16 markedly reduced cell growth in PCa cells."
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"Indeed a knockdown of USP16 or an over-expression of its catalytically inactive form slow down cell growth and interfere with mitosis, suggesting that USP16 is the H2A-DUB responsible for histone H2A [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These results demonstrate that inhibiting USP16 significantly suppressed PCa cell growth in vivo."
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