IndraLab

Statements

OTUD5 leads to the ubiquitination of GPX4. 4 / 4
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"Silencing OTUD5 increased GPX4 ubiquitination in HBMECs co-cultured with siTHBS1-AMφ-exo (Fig.  xref G)."
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"Additionally, we found that knockdown or depletion of OTUD5 markedly increased GPX4 ubiquitination (Figure  xref )."
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"In addition, OTUD5 rescued the GPX4 de‐ubiquitination phenotype in HEK293T cells, while E3 ligases MIB2, NEDD4L, and STUB1 didn't affect the ubiquitination of GPX4 caused by 4‐HNE (Figure S6A–D, Supporting Information)."
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"Silencing OTUD5 increased GPX4 ubiquitination in HPMECs co-cultured with siGBP2-SMφ-EVs ( xref H)."
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