IndraLab

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AR activates USP12. 2 / 2

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"USP12 in the presence of its cofactors Uaf-1 and WDR20 deubiquitinates AR to enhance AR protein stability and transcriptional activity [71] USP12 in complex with Uaf-1 and WDR20 also abrogates phospho[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Akt inhibition abrogated S213 phosphorylation of AR and decreased the ability of Usp12 to stabilise AR protein levels."

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IndraLab

Statements

AR activates USP12. 2 / 2

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