IndraLab

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Luteolin inhibits MAPK8. 6 / 7
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"In vitro kinase assay data shows that JNK1 activity was significantly suppressed by luteolin, but there was no significant change in JNK2 activity (XREF_FIG A and B)."
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"Luteolin significantly reduced the activity of JNK1 and p90RSK, but not JNK2 and ERK2."
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"Our in vitro kinase assay results indicate that luteolin significantly inhibits JNK1 and p90RSK2 activity, but not that of JNK2 and ERK2."
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"In vitro kinase assay data revealed that luteolin significantly suppressed JNK1 and p90RSK activity, but not that of JNK2 and ERK2."
23551430
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"Luteolin was able to inhibit the activation of c-Jun N-terminal kinases (p-JNK), p38 mitogen-activated protein kinases, glial fibrillary acidic protein (GFAP), and ionized calcium adaptor molecule 1 (IBA1) in the cortex and hippocampus of mice."
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"Hesperetin appeared to increase pERK-1 and -2 ( Fig. 8 A), while luteolin reduced p-JNK ( Fig. 8 B)."
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