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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 inhibits cell growth. 3 / 3

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"For instance, downregulation of USP18 reduces acute promyelocytic leukaemia cell growth and induces apoptosis, whereas silencing USP18 in glioblastoma cells enhances IFN induced apoptosis [XREF_BIBR]."

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"The CCK8 and EdU assay data showed that silencing USP18 obviously suppressed pancreatic cancer cell growth in vitro (XREF_FIG, XREF_FIG)."

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"Subsequently, we demonstrated that knockdown of USP18 inhibited HCC cell growth and caused cell-cycle arrest and early apoptosis."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...