IndraLab

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INS increases the amount of KCNH2. 4 / 4
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"Furthermore, insulin promotes the expression of the hERG channel and ameliorates the high-glucose-induced inhibition of the hERG channel."
26303164
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"XREF_BIBR Furthermore, insulin treatment restored expression of HERG in diabetic myocardium."
20102896
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"Recently, insulin and dexamethasone have been shown to increase mature hERG expression in the plasma membrane by inhibiting the degradation and enhancing recycling of hERG protein ( Lamothe and Zhang,[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In addition, we demonstrated that 100 nM insulin up-regulated the expression of the hERG channel and rescued the hERG channel repression caused by high glucose."
26303164