IndraLab

Statements

TRIM14 activates USP14. 3 / 3
| 3
reach
"The induction of TRIM14 by IFN-I accelerates cGAS stabilization by recruiting USP14 to cleave the ubiquitin chain of cGAS at lysine (K)414 (18)."
40028324
reach
"More recently, TRIM14 has been shown to promote cGAS stability by recruiting the deubiquitinase USP14 and preventing autophagosomal targeting of cGAS."
32404352
reach
"Compared to the direct activation of cGAS, TRIM14 indirectly increases cGAS stability by recruiting the deubiquitinase USP14 to cleave the K48-linked polyubiquitylation of cGAS [35]."
36498930