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ATXN3 deubiquitinates HDAC3. 3 / 4
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"Besides, ATXN3 positively regulates type I IFN antiviral response by deubiquitinating and stabilizing HDAC3 [33]."

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"Moreover, ATXN3 deubiquitinates HDAC3, thereby enhancing HDAC3 protein stability."

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"Likewise, ATXN3 has been shown to exacerbate type I antiviral response via the deubiquitination and stabilization of histone deacetylase 3 (HDAC3) (Feng et al., 2018)."