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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP9X activates KRAS-G12D. 2 / 2

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"The FAM labelled probe targeted the KRAS G12D allele, while the CAL Fluor Orange560 labeled probe (VIC alternative probe) targeted the WT allele."

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"In these models, genetic inactivation of Usp9x (either by insertional mutagenesis or Pdx1-Cre mediated deletion) was found to enhance oncogenic Kras G12D in accelerating tumourogenesis and cancer progression [XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...