IndraLab

Statements


USP9X activates KRAS-G12D. 2 / 2
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"The FAM labelled probe targeted the KRAS G12D allele, while the CAL Fluor Orange560 labeled probe (VIC alternative probe) targeted the WT allele."

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"In these models, genetic inactivation of Usp9x (either by insertional mutagenesis or Pdx1-Cre mediated deletion) was found to enhance oncogenic Kras G12D in accelerating tumourogenesis and cancer progression [XREF_BIBR]."