IndraLab

Statements

OTUB1 inhibits TP53BP1. 4 / 4
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reach
"The depletion of OTUB1 results in persistent ubiquitin chain formation at DSB sites, and the overexpression of OTUB1 inhibits 53BP1 IRIF, suggesting that OTUB1 is involved in RNF8- and RNF168 dependent DDR."
26983989
reach
"Accordingly, the overexpression of OTUB1 inhibits K63 chain accumulation and 53BP1 IRIF."
30831436
reach
"Both OTUB1 and the catalytically inactive OTUB1 C91S mutant completely suppressed accumulation of 53BP1 at DSBs."
24560272
eidos
"Depletion of OTUB1 leads to persistent 53BP1 after DNA damage ."
31164001