IndraLab

Statements

ENY2 binds USP22. 3 / 9
6 | 2 1
reach
"Further, Pfam analysis of protein domain structures confirmed that in addition to the catalytic UCH domain, both USP27X and USP51 have an N-terminal Znf-UBP domain highly similar to that found in USP22, which is critical for USP22 interaction with ATXN7L3 and ENY2 and deubiquitination activity (XREF_FIG and XREF_SUPPLEMENTARY)."
27132940
reach
"Streptavidin pull-down of SFB-tagged PCAF validated our AP-MS, as interactions between PCAF and the SAGA DUB components USP22, ENY2, and ATXN7L were observed (Fig. 4B)."
31753913
sparser
"The association of USP22 and ENY2 in the same TFTC/STAGA module would therefore suggest that two activities, histone deubiquitination and mRNA export, may also be coregulated within this complex."
18206972