IndraLab

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Pbp1 inhibits PAN2. 4 / 4
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"Further analysis should be needed to elucidate the physiological role of Pan2 inhibition by Pbp1 in the stationary phase."
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"Consistently, we found that the shortening of the LRG1 poly (A) tail length in the ccr4Delta pbp1Delta mutant required Pan2 deadenylase in vivo, and that Pbp1 inhibited Pan2 activity only in the stationary phase but not in the log phase."
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"Pbp1 negatively regulates Pan2 activity in the absence of Ccr4 in the stationary phase."
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"If Pan2 activity is inhibited by Pbp1, the LRG1 poly (A) tail length in the ccr4Delta pbp1Delta pan2Delta triple mutant would be longer than that in the ccr4Delta pbp1Delta double mutant in the stationary phase."
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