IndraLab

Statements

PSMD14 activates IL1B. 2 / 2
| 2
reach
"Unexpectedly, upon treatment with the inflammasome activators, POH1 deficiency did not lead to an increase in pro-caspase-1 cleavage in LPS primed BMDMs, but enhanced cleavage of pro-IL-1beta, as measured by the mature forms of pro-caspase-1 and pro-IL-1beta."
30315153
reach
"POH1 deficiency in macrophages enhances mature IL-1beta production without significant alterations in inflammasome priming and ASC-caspase-1 activation."
30315153