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KCNH2 inhibits cisapride. 4 / 4
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"These results indicate that cisapride produced anti-hypertrophic effects in neonatal rat ventricular cells.To unravel the mechanisms underlying the anti-hypertrophic property of cisapride, we first te[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Compared to PSS, the IC 50 values, conducted at room temperature, of the classic hERG blocking drugs cisapride, moxifloxacin, and terfenadine were shifted to the right by an extent predicted by their known plasma protein binding, but we did not detect any differences in IC 50 s between male and female serum."
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"High-affinity hERG channel blocking drugs E4031, astemizole, cisapride and quinidine all produced reverse effects, and the rescue was dependent on their interaction with F656."
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"Diseases characterized by an elevated baseline of arrhythmia such as LQT and HCM exhibited a particular propensity for exhibition of drug induced EADs by hERG blockade with cisapride."
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