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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

ATXN3 decreases the amount of PTEN. 3 / 3

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"In addition, up-regulation of Ataxin-3 inhibited the expression of PTEN and activated the AKT and mTOR pathway."

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"The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells."

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"Moreover, a recent study by Coulson and colleagues 46 provided convincing evidence that ataxin-3 restricts the transcription of the tumor suppressor PTEN."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

ATXN3 decreases the amount of PTEN. 3 / 3

Our Sources:

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