IndraLab

Statements


ATXN3 decreases the amount of PTEN. 3 / 3
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"In addition, up-regulation of Ataxin-3 inhibited the expression of PTEN and activated the AKT and mTOR pathway."

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"The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells."

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"Moreover, a recent study by Coulson and colleagues 46 provided convincing evidence that ataxin-3 restricts the transcription of the tumor suppressor PTEN."