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Δ inhibits UCHL3. 2 / 2

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"Other investigators have reported that cyclopentone PGs inhibit cellular DUB activities: UCHL3 was found to be inhibited by Δ12-PGJ2 ( Li et al., 2004 ) and UCHL1 by 15Δ-PGJ2 ( Liu et al., 2011c )."

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"Treatment with Δ -PGJ in cells also inhibited UCH-L1 and UCH-L3 without alteration of proteasomal activity, indicating that prostaglandins can be suitable for neural disorder therapy [95]."

| PMC

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Δ inhibits UCHL3. 2 / 2

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