IndraLab

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TP53 decreases the amount of USP22. 3 / 3
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"We have found H O -induced p53 expression inhibits the transcription of USP22, which otherwise deubiquitinates and stabilizes FASN."
36333288
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"In p53 wild-type colorectal cancer (CRC) cells, hydrogen peroxide (H 2 O 2 )-induced p53 expression represses the transcription of deubiquitinase USP22, which otherwise deubiquitinates and stabilizes Fatty Acid Synthase (FASN), and thus inhibits fatty acid synthesis."
36333288
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"P53 transcriptionally represses USP22 expression under H 2 O 2 treatment."
36333288