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PPARG increases the amount of CYLD. 3 / 3
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"J Biol Chem 2005; 280 : 12888-12895.10 Pseftogas A, Gonidas C, Mosialos G. Activation of peroxisome proliferator activated receptor gamma in mammary epithelial cells upregulates the expression of tumor suppressor Cyld to mediate growth inhibition and anti-inflammatory effects."
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"The induction of Cyld expression by PPAR-γ activation raised the possibility for a regulatory role of CYLD in lipid metabolism."
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"These results indicate that the PPAR-γ activator TZD can induce the expression of Cyld in human mammary epithelial cell lines.PPAR-γ can bind DNA as a heterodimer with RXR."
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