IndraLab

Statements

Gallic acid inhibits IFNB1. 5 / 5
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"GA treatment inhibits IFN-beta production by targeting regulatory elements of the IFN-beta promoter."
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"Our finding that GA prevents IFN-beta synthesis in M2 monocytes is consistent with the earlier demonstration that STAT1 phosphorylation is reduced upon activation in these cells."
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"The component formula of GA, MT and TS inhibited IFN-β and ISGs in PRRSV infected PAMs, but did not in un-infected PAMs."
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"16 Taken together, these results demonstrate that GA treatment inhibited IFN-beta production by interfering with activation of transcription factors participating in formation of the IFN-beta enhanceosome."
26601118
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"Our qPCR results showed that MT, GA and TS promoted IFN-β and interferon stimulated genes (IFIH1, IFIT3 and ISG15) expression in un-infected PAMs with varying degrees, suggesting that GA, MT and TS inhibit the PRRSV replication by targeting IFN-β pathway."
35568854