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Statements

OTUD7B activates Wnt. 3 / 3
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eidos
"Screening candidate DUBs from the human DUB library , we discovered that OTUD7B interacts with LEF1 and activates Wnt signaling ."
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"As a result, we hypothesized that OTUD7B promotes Wnt signaling by facilitating the nuclear localization of LEF1 and/or its interaction with β-catenin within the nucleus."
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"Screening candidate DUBs from the human DUB library, we discovered that OTUD7B interacts with LEF1 and activates Wnt signaling."
37371581